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Hemodialysers were contaminated with Azodi-Dextran and their performance was assessed after 10 min incubation in vitro. Blood clearance for such hemodialysers was significantly reduced, yet their dialysate clearance was improved as compared to dialysers pre-incubated with similar concentrations of dextran. Light scattering and atomic force microscopy revealed that Azodi-Dextran immobilization occurred on the surface of the hemodialyzers, and this was accompanied by a slight decrease in membrane thickness and an increase in roughness. The data demonstrate that Azodi-Dextran has the potential to improve the efficiency of hemodialysis in terms of both blood and dialysate clearances.Autoimmune reactions to parathyroid alloantigens in autoimmune parathyroid disease. In this study we describe a series of patients who had autoimmune parathyroid disease (AIPD) and autoantibodies that reacted with the 4 major high molecular weight isoforms of human parathyroid antigen. 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